This work aims to carry out an ethnography of the memories of the Covid-19 pandemic, its social impacts and its long effects that persisted in the post-pandemic moment, among Fulni-ô indigenous people, located in the northeast of Brazil, and the P`urhépecha comunity called Caltzontzin, located in the municipality of Uruapan in the state of Michoacán, that is situated in the central western region of Mexico. This article articulates elements developed in the context of my doctorate and post-doctorate research, which is still in progress. This comparative research also aims to identify and understand local strategies for coping with the pandemic, including the role played, in the pandemic and post-pandemic contexts, by the indigenous medical systems and its self-care practices, as well as the way in which they were public policies are carried out, especially health and social protection. The theoretical foundation of this research is based on work in the field of medical anthropology (Menéndez, 2003), indigenous health (Langdon, 2004: Garnelo, 2022), memory (Jelin, 2002), as well as studies of interethnic relations and processes of territorialization (Oliveira Filho, 1998, 2004; Teófilo da Silva, 2005) and colonialism (Batalla, 1990, Casanova, 2002). The memories of Fulni-ô people revealed the importance that indigenous medicine, the performance of the Ouricuri ritual and the communality played in curing the symptoms of Covid-19 and maintaining life. It also revealed the difficulty that indigenous people living in the municipality, where the Indigenous Land is located, suffered in accessing the vaccine, demonstrating how the pandemic has deepened racism and the inequities in which they live. The memories of the pandemic by Tata Toral, the traditional doctor who was willing to collaborate with the research, showed the valuable role that P`urhepecha traditional medicine played. It was the most accessible and used therapeutic resource by the population of his comunity.