Himalayan Nepal, predominantly Hindu, navigates a dynamic path of social transformation and modernization. Education serves as a pivotal vehicle in this journey. The global education system significantly influences Nepal's educational landscape, with institutional plans supported by international donors. Amidst this, indigenous and ancient knowledge finds its place within national institutions, and Gurukul education stands out. To explore gender relations in mainstream Gurukul education in Nepal. This ethnographic study was carried out by applying observation and interview methods in the site and out sites. The findings reveal the mainstreaming process has witnessed the emergence of more than two hundred Vedic Gurukuls, nurturing scholars of the Vedas, ritual experts, and Sanskrit literature. However, Gurukuls specifically for girls remain scarce. Only three Gurukuls for girls were adequate for the feminization process struggle. This ethnographic study delves into the struggle faced by girls seeking equal education within the Gurukul system. Traditionally, Vedic education has been associated with Sanskritization—a process where lower castes emulate upper castes' lifestyles for upward social mobility. Neo-Sanskritization takes a distinct path. It harmonizes ancient wisdom with global subjects, transcending caste boundaries. Neo-Sanskritization facilitates social mobility and empowers individuals economically, educationally, and in terms of gender. Three primary streams exist within the Gurukul institutions: Veda chanting and ritualism, Vedic or Puranic storytelling, and Sanskrit literature. Some girls are prepared explicitly for ritual professions. Notably, a team produced from a girls' Gurukul now provides priestly services akin to male priests. However, divisions persist within the Vedic scholarly community regarding female mantra chanting. As traditional agrarian practices decline, the constitution reserves public priestly positions, and technology demystifies ancient mantras and literature. A gender-sensitive segment of society fervently advocates for female priests. This paper sheds light on the gradual dismantling of caste and gender barriers and the demand for female priests in the country.