Female genital schistosomiasis (FGS) remains an important public health problem with an estimated 16-56 million women affected, although the true burden remains unknown due to under- and misdiagnosis. Chronic FGS can lead to severe complications for women’s sexual and reproductive health. FGS is a disease primarily affecting low-income women living in rural areas that has historically been neglected in global and national health agendas relative to other diseases with similar prevalence. The multidisciplinary DUALSAVE-FGS project is piloting a novel multispectral colposcope and validating its performance in detecting FGS in vivo by conducting a clinical trial in three countries where schistosomiasis in endemic: Mozambique, South Africa and eSwatini. An ethnographic study of how healthcare providers and patients manage cases of FGS or FGS-compatible cases is ongoing in rural areas of southern Mozambique prior to the start of the clinical trial. This is the first ethnographic and non-clinical study conducted in Mozambique on FGS to date. A broad range of participants are being engaged through informal conversations and interviews, including healthcare providers, patients presenting at facilities with FGS-compatible symptoms, female patients diagnosed with schistosomiasis, traditional birth attendants, community health workers, and male relatives of patients diagnosed with FGS or being treated for FGS-compatible symptoms. The fieldwork is generating rich and in-depth insights into how patients and healthcare providers conceptualise FGS in terms of its aetiology and modes of transmission; how patients experience FGS as a chronic illness affecting their sexual and reproductive health; how patients make sense of the process of seeking care for FGS-compatible symptoms, including the perspective of other actors involved in the decision-making; how healthcare providers, community health workers and traditional birth attendants manage and experience the provision of care for these patients, as well as the networks of care that form around FGS patients.